Is HCM genetic?
HCM in humans, in the majority of cases, is an inherited genetic disorder, with over 130 genetic mutations already identified.
It is now also believed that HCM in cats could also be genetic. Recently, genetic mutations have been identified in both the Maine Coon and Ragdoll breeds of cat, and there is ongoing work looking for further mutations in the Norwegian Forrest Cat and Sphinx. Within the Maine Coon breed, approximately one third of tested cats are positive for the mutation. However, not all Maine Coons with HCM are positive and this particular mutation has not been identified in any cats other that Maine Coons and their progeny. The mutation identified in the Ragdoll is located within the same gene as the Maine Coon mutation. However, this mutation is different to that identified in Maine Coons and to date, there is no information on the incidence of this mutation within the Ragdoll breed.
Genetic testing of affected cats can be useful in identifying which cats carry the mutation. Whilst a positive test result means that the cat is genetically predisposed to HCM, unfortunately a negative test only means that the cat does not have that one particular mutation. It does not mean that the cat being tested doesn’t have HCM.
Is there a screening scheme available to detect cardiomyopathy in cats?
The Feline Advisory Bureau, together with the Veterinary Cardiovascular Society (VCS) have set up a scheme to detect the presence or absence of hypertrophic cardiomyopathy(HCM). See below..
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